Tumor mutational burden is not predictive of cytotoxic chemotherapy response
نویسندگان
چکیده
منابع مشابه
Tumor Mutational Burden as an Independent Predictor of Response to Immunotherapy in Diverse Cancers.
Immunotherapy induces durable responses in a subset of patients with cancer. High tumor mutational burden (TMB) may be a response biomarker for PD-1/PD-L1 blockade in tumors such as melanoma and non-small cell lung cancer (NSCLC). Our aim was to examine the relationship between TMB and outcome in diverse cancers treated with various immunotherapies. We reviewed data on 1,638 patients who had un...
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ژورنال
عنوان ژورنال: OncoImmunology
سال: 2020
ISSN: 2162-402X
DOI: 10.1080/2162402x.2020.1781997